Publication – Enhanced catalysis under flow conditions using SiliaBond functionalized silica gels
Catal. Sci. Technol., 2011,1, 1600-1604
- Valerica Pandarus, Genevieve Gingras, François Béland, Rosaria Ciriminna and Mario Pagliaro
- SiliCycle Inc., 2500, Parc-Technologique Blvd, Quebec City, Quebec, Canada G1P 4S6 & Istituto per lo Studio dei Materiali Nanostrutturati, CNR, Via U. La Malfa 153, 90146 Palermo, Italy
The work published in this paper was performed on an Asia flow chemistry system and shows an improved yield and selectivity with flow chemistry over traditional batch techniques.
Abstract: Functionalized silica gels of the SiliaBond series such as acid, base, and nucleophilic catalysts can be effectively employed in solid-state syntheses under flow conditions. Comparison of reactions under batch and flow chemistry generally shows that reactions under flow result in enhanced selectivity and conversion.